GDF10 and Alzheimer disease: The SLC6A12 gene, for example, is a neurotransmitter transporter which has recently been screened as a hub gene, showing high expression in AD patients (Zou et al., 2023) studies have shown GDF10 had an important role in supporting neuronal survival (Li et al., 2010) and reducing neuroinflammation (Li et al., 2015).