Additionally, the presence of CD27 on CD24+ CD27+ cells was associated with an increased risk across all three lung cancer subtypes (for LUAD, ORIVW =1.039; 95% CI: 1.006–1.072; PIVW =0.019; for LUSC, ORIVW =1.041; 95% CI: 1.003–1.080; PIVW =0.032; for SCLC, ORIVW =1.072; 95% CI: 1.010–1.137; PIVW =0.022). This evidence concerns the gene CD27 and lung cancer.