IL4 and tropical spastic paraparesis: Following up on the initial finding of low IL-10 and IL-4 as independent risk factors for iHAM, we further explored a previously proposed biomarker (CXCL10), as well as a large panel of 37 pro-and anti-inflammatory cytokines, chemokines and immune mediators, of which 30 had not been studied at the protein level before in HAM patients.