ATXN3 and essential thrombocythemia: Limited literature suggested a prevalence of 0.5% (1/177) ATXN3 in ET.38 However, pathogenic or intermediate expansions were not reported in 10 common degenerative hereditary ataxias among 323 ET patients in the study conducted by Louis et al.,39 and neither Nicoletti et al. 40 nor Chen et al. 41 found PPP2R2B in ET patients.