Patients presented with MI had significantly higher peak serum/plasma concentrations of MRP8/14 (3.44 vs. 2.00 μg/mL for noncardiac, p < 0.001). The AUC for diagnosis of MI was 0.55 (95% CI 0.51−0.60). Also, the AUC of MRP8/14 for diagnosis of ACS was 0.57 (95% CI 0.51−0.63). The gene discussed is S100A8; the disease is myocardial infarction.