TLR4 and coronary artery disorder: Serum S100A8/A9 levels were positively correlated with TLR‐4 (r = 0.754, p = 0.022) and COX‐2 levels (r = 0.602, p = 0.036) in the ACS group and with TLR‐4 (r = 0.586, p = 0.045) in the CHD group. There was no obvious correlation between S100A8/A9 and COX‐2 levels in the CHD patients (r = 0.078, p = 0.171). Peripheral blood S100A8/A9 levels were associated with ACS and also with CHD.