Moreover, there is a significant correlation between the expression level of IL6R and many immune cells, such as T cells, macrophages, neutrophils, DC cells, etc. An interesting and striking observation here is that the correlation between IL6R and immune cells in colorectal cancer and lymphoid neoplasm diffuse large B‐cell lymphoma (DLBC) is significantly higher than that in other malignancy. This evidence concerns the gene IL6R and diffuse large B-cell lymphoma.