Recently, re-analyzing previously published transcriptomic data classified SCLC into four subtypes [14]; in addition to the previously identified subtypes with the ASCL1 (SCLC-A), NeuroD1 (SCLC-N), and POU2F3 (SCLC-P) signatures, a new subtype (SCLC-I) characterized by the expression of inflammation gene signatures was uncovered. Here, POU2F3 is linked to small cell lung carcinoma.