APOC3 and familial chylomicronemia syndrome: Furthermore, a study reported that serum TGs were significantly higher in patients with asthma, even after adjusting for factors such as BMI, blood eosinophils, and statin use [52].Volanesorsen is a novel antisense oligonucleotide inhibitor of APOC3 mRNA developed for the treatment of familial chylomicronemia syndrome [54, 55].