Subsequently, the METTL3-METTL14-WTAP complex functions to promote BC progression by depositing m6A modification on RNAs, which primarily depends on its methyltransferase activity that is supported by the catalytic role of METTL3, the structural role of METTL14, as well as the adaptor role of WTAP. This evidence concerns the gene METTL3 and breast cancer.