JARID2 and cancer: Kaplan-Meier survival plot also showed that OSCC patients with high expression of JARID2 protein had a significantly worse prognosis (p = 0.039) (Fig. 1C), and JARID2 expression was higher in normal tissue adjacent to cancer in patients than in cancer tissue (Fig. 1D).Differential gene expression analysis based on the TCGA database revealed a significant increase in JARID2 expression in OSCC samples compared to normal oral mucosal samples (p < 0.001) (Fig. 1E).