In immune-related functional analysis, we found that the immune cells, which has a infiltration positively correlated with JARID2 expression, comprised not only immune cells that exerted anti-tumor functions (CD56bright natural killer cell, activated CD4 T cell, central memory CD4 and CD8 T cell, activated dendritic cell), but also immune cells that exerted immunosuppressive and tumor promoting functions (type 2 T helper cell, neutrophil, plasmacytoid dendritic cell). The gene discussed is CD4; the disease is neoplasm.