GBE1 and neoplasm: GBE1 overexpression dramatically enhanced tumor growth since the tumor size was larger in GBE1 overexpression group when compared to negative control group (Fg. 2I, J, Fig. S2A), and the body weight changes of nude mice in each group were shown in Fig. 2K. Taken together, GBE1 enhanced cell growth both in vitro and in vivo.