MALAT1 and Anxiety: We speculated that HCN channels in the LHb serve a crucial role in regulating depressive‐like behaviors, while anxiety‐like behaviors in SNI 6w mice might be associated with other neural mechanisms in the LHb or related to other brain regions, such as the amygdala,56, 57, 58, 59 hippocampus,60 and prefrontal cortex.61, 62