According to the updated Expert Consensus on the Diagnosis of Liver Fibrosis by Transient Elastography in 2018, cirrhosis was considered for CHB patients with normal bilirubin and ALT < 5 × ULN at LSM 17.00 kPa, and cirrhosis was considered for CHB patients with normal bilirubin and ALT at LSM 12.00 kPa8. The gene discussed is GPT; the disease is Cirrhosis.