MT-RNR1 and Hodgkins lymphoma: In 1993 Fischel-Ghodsian and colleagues reported discovery of the m.1555A > G variant in the MT-RNR1 gene encoding mitochondrial 12S rRNA in patients with aminoglycoside antibiotics induced HL (deafness, aminoglycoside-induced, OMIM: 561000.0001)6–8.