At diagnosis, the combined DNA ploidy and PTEN status was associated with GGG (p < 0.0001), cT stage (p = 0.036), CAPRA score (p = 0.0006), percentage of positive biopsy cores (p < 0.0001) and maximum cancer extent within a biopsy core (p < 0.0001), (Supplementary Table S3). Here, PTEN is linked to cancer.