Furthermore, DCAF15 mRNA expression was significantly higher in AML patient samples compared to normal hematopoietic stem cells (HSC) (Fig. 1e), and significantly higher in AML cell lines compared to solid tumor cell lines according to the Cancer Cell Line Encyclopedia (CCLE)37 (Supplementary Fig. 1e), indicating a potential cancer-promoting function of DCAF15 in AML. Here, DCAF15 is linked to cancer.