SNCA and Parkinson disease: Disrupted cellular and molecular processes, including diminished lysosomal activity, endoplasmic reticulum stress-related mechanisms, and the occurrence of inflammatory, autophagic, and apoptotic-like cell death events, are linked to the formation of alpha-synuclein fibrillar aggregates (Kalia et al. 2013; Vidyadhara et al. 2019; Maiti et al. 2017).These processes collectively contribute to dopaminergic neurodegeneration in Parkinsons disease (PD) (Zhang et al. 2017).