The pathogenesis of PD involves two main hallmarks: the depletion of dopaminergic neurons in the substantia nigra pars compacta region and the accumulation of intracellular aggregates known as Lewy bodies, primarily composed of the alpha-synuclein protein in dopaminergic neurons, leading to their degeneration (Wakabayashi et al. 2013). This evidence concerns the gene SNCA and Parkinson disease.