Interestingly, despite the changes in connectivity observed between limbic structures implicated in anxiety (Fig. 6N–P), Eed-cHet and Eed-cKO mice did not spend more time in the light or dark component compared to controls (Fig. 7B), although Eed-cKO mice did have reduced frequency in the number of times they moved between compartments (Fig. 7C). Here, EED is linked to Anxiety.