HNF1B and maturity-onset diabetes of the young: On the other hand, lipid hyper-responders exhibited elevated hepatocyte nuclear factor 1-beta (HNF1B), the gene product underlying a rare form of diabetes, maturity onset diabetes of the young (MODY5), sulfotransferase family 1A member 1 (SULT1A1), and platelet-derived growth factor receptor alpha (PDGFRA) (Figure 4C).