NID2 and cancer: To do this, we coinjected a 1:3 ratio of luciferase-expressing KPC cancer cells and CAFs (GFP KRAB or B500 NID2 KRAB) into the pancreas of NOD.Cg-PrkdcscidIL2rgtm1Wjl/SzAusb (NSG) mice, as previously achieved (Fig. 6A) (15, 28, 29, 64).