NID2 and familial pancreatic carcinoma: By interrogating publicly available scRNA-seq data from specimens of both the KPC mouse model (8) and patient with PDAC (59), we confirm that NID2 is largely expressed by stromal cells, including fibroblasts and stellate cells, which are the main contributors to matrix deposition and remodeling in pancreatic cancer (4, 6, 49, 67).