HOTAIR and chronic kidney disease: Due to the lack of research evidence on the mechanism underlying the relation between genetic variants of HOTAIR and CKD risk, in this study, we aimed to investigate the role of specific polymorphisms within the HOTAIR gene—namely, rs4759314, rs920778, rs12826786, rs1899663, and rs3816153 (Scheme 1)—in the pathogenesis of CKD.