Notably, the rs1899663 variant of the HOTAIR gene conferred an increased risk of CKD under codominant (TT vs. GG, OR = 2.24, 95% CI = 1.08–4.63, p = 0.030) as well as the allelic (T vs. G, OR = 1.46, 95% CI = 1.05–2.03, p = 0.023) modes of inheritance. This evidence concerns the gene HOTAIR and chronic kidney disease.