MALAT1 and cancer: Bone marrow MSC-EVs show therapeutic efficacy toward osteoporosis and osteolysis achieved by cargos including miR-150–3p,194 miR-186195, miR-150–5p,196 MALAT1,197 miR-6924–5p.198 Spinal cord injury is another disease that is studied for the use of BM-MSC-EVs through regulation of inflammation199–202 and apoptosis.203–205 As the most popular candidate for cancer related research, BM-MSC-EVs are mostly studied in cancers arisen in the bone marrow.