In contrast, the patient's age, BMI, tumor stage, and resection margin did not show significant associations. However, in multivariate analysis, only an NRS score equal to or greater than three, and low serum albumin (<3.5) had a statistically significant correlation with major post-operative complications (OR- 1.647 {95% confidence interval: 1.223 -2.219}) (Tables 3, 4). The gene discussed is ALB; the disease is neoplasm.