PRTN3 and vasculitis: The clinical symptoms of PTU-induced vasculitis may include cutaneous hyperpigmentation, ecchymoses, purpura, lesions, and joint, renal, or pulmonary involvement with a difference in severity among patients [10]. Although the association of PTU-induced ANCA vasculitis has been well-documented, the association of PTU-induced IgA vasculitis remains unclear and possibly underreported [9]. Regarding PTU-induced ANCA vasculitis, the presence of a higher level of anti-MPO antibodies compared to anti-PR3 antibodies has been the more common presentation of this adverse reaction.