In streptozotocin (STZ)-induced male C57BL/6 mice with diabetes, the subconjunctival injection of MCC950 promoted diabetic corneal wound healing, accelerated re-epithelialization, improved corneal sensation and nerve fiber density, and reduced corneal NLRP3 and IL-1β mRNA transcription and IL-1β protein levels [96]. Here, NLRP3 is linked to diabetes mellitus.