Examples include Aβ plaques and neurofibrillary tangles in AD, α-synuclein in Parkinson’s disease, polyglutamine repeats in Huntington’s disease, superoxide dismutase 1 in amyotrophic lateral sclerosis, TAR DNA-binding protein 43 (TDP-43) in limbic-predominant age-related TDP-43 encephalopathy, and prion diseases (Sweeney et al., 2017). Here, TARDBP is linked to amyotrophic lateral sclerosis.