LGALS9 and rheumatoid arthritis: Univariate logistic regression analysis showed that time of morning stiffness (TMS) >60mins, Pain VAS >4 (median Pain VAS), HAQ >1 and Gal-9 >11.6 ng/mL were positively associated with high disease activity in patients with RA, while treatment with csDMARDs was associated with a lower risk of high disease activity in patients with RA.