Comatose state, decreased RBC, Hb and HCT. Platelet count: 60.000/mm3. LDH, AST and ALT levels were 10, 80 and 100 times higher the normal range. The diagnosis was thrombotic thrombocytopenic purpura and hemolytic uremic syndrome. This evidence concerns the gene GPT and thrombotic thrombocytopenic purpura.