ABCC3 and neoplasm: reported that astragaloside IV enhanced the sensitivity to cisplatin chemotherapy by increasing tumor cell apoptosis, slowing tumor growth and inhibiting the expression of multidrug resistance-associated proteins in tumor cells from enhancing the antitumor effect of cisplatin on hepatocellular carcinoma, which provided new insights into the combined use of chemotherapeutic agents and natural ingredients in the treatment of cancer (51).