One such is SHBG which has been a subject of extensive studies due to its strong association with GDM and its ability to predict GDM development18–21 even in similar cohorts from the present study population.22,23 Considering the established pathological links between SHBG and GDM,8 as well as its ability to predict the disease, the investigators hypothesize that SHBG may be a valuable tool for diagnosing GDM. This evidence concerns the gene SHBG and gestational diabetes.