PDS (including Rg3, Rh2, Rb1, Rb2, Rc, Rd, CK, and PPD) and PTS (including Rg1, Rg2, Rh4, Re, and nR1) could activate the immune responses in some diseases, such as lung injury, liver injury, and asthma (Figure 4); however, PDS (including Rg3, Rb1, Rd, and CK) and PTS (R1 and R6) showed immunosuppressive properties in some diseases, such as rheumatoid arthritis (RA), septic shock, and sepsis (Figure 5) [57]. The gene discussed is RGN; the disease is rheumatoid arthritis.