TRIM26 and differentiated thyroid carcinoma: In Papillary Thyroid Carcinoma (PTC), TRIM26 has been reported to be significantly down-regulated in tissues and cell lines, and overexpression of TRIM26 has been reported to significantly inhibit the phenotypes of PTC cells, such as proliferation, migration, and EMT, as well as the activation of glycolysis and PI3K/Akt signaling pathways [78].