Three of them presented retinopathy associated with the homozygous c.1354dupT (p.Tr452 Leufs*13) mutation in the PROM1 gene inherited in an autosomal recessive manner, and were selected for the generation of iPSC lines, as they exhibited three distinct phenotypes: IRD1 is a 47-year-old female with the CORD phenotype (Fig. 3A); IRD2 is a 54-year-old female with the RP phenotype (Fig. 3B); and IRD3 is a 20-year-old male with the STGD4 phenotype (Fig. 3C). Here, PROM1 is linked to retinal disorder.