All potential predictive factors including age, pathology, hypertension, diabetes, clinical stage, ER status, PR status, HER-2 status, Ki-67, type of surgery, radiotherapy, adjuvant chemotherapy, endocrine therapy, target therapy, CEA, CA153, NLR, PLR, and HALP were included in Cox regression survival analysis. The gene discussed is MKI67; the disease is hypertensive disorder.