On chromosome 16, two SNVs (rs12445650, rs58726213) showed strong LD with PD GWAS-SNV rs12600861 (r2 = 0.801, D′ = 0.901) within cCRE peaks linked to the PD GWAS-DEG RNF40 in Exc5 nuclei (Fig. 7C, Table S11). This evidence concerns the gene RNF40 and Parkinson disease.