Decreased folate content was apparent in Tg(lfabp:mCherry/hsp:eGFP-γGH) larvae (FD larvae) and the liver of Tg(lfabp:mCherry/hsp:eGFP-γGH) adult fish (FD adult fish), confirming the successful induction of FD (Fig. 2a). This evidence concerns the gene GGH and Fabry disease.