KRT8 and neoplasm: Representative immunohistochemistry of the epithelial marker CK8 revealed a reduction in number of CK8-positive tumor cells within the trabecular zone of LN sections of PyMTSB2−/− mice (2.95 ± 0.67%) compared with that of PyMTWT mice (6.37 ± 0.98%) (Fig. 6A bottom and Table 1, P = 0.02).