In our previous study of transcriptome analysis of mammary tumors of PyMTSB2−/− mice, the expression levels of cancer immune modulated genes (ANXA3, CCL17, CXCL13, CXCR3, IFN-γ, NR4A1, and SEMA3a) were significantly changed [16]. The gene discussed is IFNG; the disease is breast cancer.