IL18 and cancer: For example, it was demonstrated that miR-92b-5p inhibitor suppressed interleukin-18 (IL-18) mediated inflammatory amplification after spinal cord injury via interleukin-18-binding protein (IL-18BP) up-regulation [34], miR-15a-3p inhibited proliferation and invasion, promoted apoptosis of cancer cells by regulating tumor protein D52 (tpd52) [35, 36].