MAP1LC3A and gastric cancer: Following the knockdown of circPTPN22 in AGS cells and the addition of the miR-6788-5p inhibitor, mRFP-GFP-LC3 double fluorescent autophagy indicator system transfection rescue experiments revealed that the inhibitor partially restored the increased number of autophagosomes and autolysosomes in GC cells after circPTPN22 interference (Fig. 4E and F).