In addition, BCL6 has also been reported as a proto-oncogene in lymphoma, acute lymphoblastic leukemia, acute myeloid leukemia, and solid cancers including breast cancer12, glioma13 and non-small cell lung cancer14 by suppressing genes involved in high-fidelity DNA repair, cell differentiation and promotes cell proliferation, anti-apoptosis, cell-cycle arrest, which are the hallmarks of cancer15,16. The gene discussed is BCL6; the disease is lymphoma.