(1) Temporal dynamics in the lungs of PTB rhesus macaques and the early role of pDCs and IFN‐reactive macrophages in the inflammatory response and initiation of TB in the lungs. (2) NK cells are not found within or near the iBALT structures of the LTBI lung. (3) Do Th1 and Th17 cells correctly localize near M.tb‐infected macrophages and mediate M.tb control. This evidence concerns the gene IFNA1 and tuberculosis.