The AUC/ROC analysis for MDW performance in detection of sepsis and septic shock according to Sepsis-3 criteria was 0.856 (95% CI 0.82–0.89), slightly below CRP and PCT [0.915 (95% CI 0.89–0.94); 0.872 (95% CI 0.83–0.92) respectively]. The gene discussed is CRP; the disease is Sepsis.