MAP1LC3A and pulmonary arterial hypertension: A significant difference in the abundance of LC3 puncta was detected when comparing the left ventricle in the end-stage PAH group (all samples had high LC3 puncta abundance, Fig. 4C) to both matched controls (all samples had low abundance or none, Fig. 4A) and early-PAH subjects (75% of samples had low abundance, and 25% had moderate abundance, Fig. 4B).