Even though DTNBP-1 does not figure in the list of top candidate genes in genome-wide association studies in schizophrenia (Schizophrenia Working Group of the Psychiatric Genomics, 2014), post-mortem investigations have revealed significantly lower expression of dysbindin-1 mRNA and protein in the prefrontal cortex (PFC) and hippocampus tissues of schizophrenia patients2,6. This evidence concerns the gene DTNBP1 and schizophrenia.