Furthermore, multivariate analysis revealed that patients operated on had 43% more CD8+ T lymphocytes than those not operated on (OR 1.43; 95% CI 1.16–1.76; p = .002) and that each centimeter increase in tumor size correlated with an increase in CD163+ macrophages of 9% (OR 1.09; 95% CI 1.02–1.17; p = .016). The gene discussed is CD8A; the disease is neoplasm.