IL6 and metabolic syndrome: BD patients show a higherprevalence of comorbid diseases with an inflammatory component, such ascardiovascular disease, diabetes, and immune-related ‘metabolic syndrome’ (Cassidy et al., 1999; Ösby et al., 2001; Weiner etal., 2011; Leboyer et al., 2012).Vadodaria et al. (2021) compared entiretranscriptomes of a cohort of healthy and BD patients, revealing that apro-inflammatory cytokine known as interleukin-6 (IL-6) was upregulated in BDpatient-iPSC-derived astrocytes compared to controls.