Another study used HPCs and recorded exposure to IL-1b to testthe potential rescue of dysregulation in the kynurenine pathway that leads todecreased neurogenesis linked to depression, using the antidepressants, sertraline,and venlafaxine, and the fatty acids, DHA, and EPA (Borsini et al., 2017). The gene discussed is IL1B; the disease is major depressive disorder.