CD8A and infection: To explore whether the defective differentiation of SLECs in BRD7-deficient mice depended on the direct role of BRD7 in CD8+ T cells, we generated chimeras by reconstituting lethally irradiated CD45.1 mice with a various 1:1 mixture of bone marrow cells of Brd7fl/fl mice and Brd7ΔT mice, followed by infection with HKx31 at 6 week after reconstitution.