Nonclassical monocytes showed a specific transcriptomic profile of 19 differentially expressed genes not shared with other cell subsets (Figure 3, B and C), including a downregulation of ETNK1, TNFSF13B, DUSP7, and IGSF6 and an upregulation of CXCR4 in RA. The gene discussed is TNFSF13B; the disease is rheumatoid arthritis.