In the KEGG enrichment analysis, the pathways identified by DEGs were primarily focused on PI3K−Akt signaling pathway, Cytokine−cytokine receptor binding, Human papillomavirus infection, AMPK signaling pathway, Regulation of lipolysis in adipocytes, Insulin resistance, PPAR signaling pathway, ECM-receptor interaction, Fatty acid degradation, Pyruvate, Tyrosine, Propanoate and Phenylalanine metabolism, among others (Fig. 3b). Here, PPARA is linked to human papilloma virus infection.