IL2 and neoplasm: The results of coculture of MDA-MB-231 cells and M1 macrophages showed that the phagocytosis of M1 macrophages was enhanced after paclitaxel administration, T cell activation assay showed that paclitaxel-treated MDA-MB-231 cells induced CD3+ T cells activation, as measured by an increase in IFN-γand IL-2 secretion, suggesting that paclitaxel may activate the anti-tumor immunity of macrophages through the pyroptosis pathway.